Testosterone pellets, also known as Testopel, are a slow-release form of testosterone supplementation that is implanted underneath the skin of the upper portion of the buttocks during a brief office procedure requiring only local numbing injection.

About eight to ten pellets, each the size of a grain of rice containing 75mg of testosterone, are tunneled underneath the skin through a 5mm skin puncture. Repeat procedures are needed about once every four months. The approach avoids more frequent dosing and limits the side effects more commonly experienced with the significant dosage spikes associated with testosterone treatments.

When to ask a Urologist about Testosterone Pellet Implantation

You should speak with a Urologist about testosterone pellet implantation if you are interested in testosterone supplementation that provides steady testosterone levels and avoids frequent applications without the risk of skin-to-skin transference of medication to family members.


Typically covered by most insurances (although coinsurance and deductibles may apply). Some insurers require trying alternative forms of testosterone supplementation before moving on to testosterone pellets. Coverage will be verified prior to proceeding. If you do not have insurance, our office will be able to give you an out-of-pocket cost estimate.


The absorption of testosterone pellets is much more reliable than with the topical gels. The pellets are very effective at normalizing testosterone levels, but dose adjustments may be required to change the number of pellets implanted during future procedures.

Possible Side Effects

Infection following this procedure is very rare and typically no antibiotics are necessary. Some men, particularly those with little fat, report the ability to feel the pellets underneath the skin when pressing the area or sitting in certain positions. Rarely, a pellet may be extruded or pushed out of the skin puncture. Other side effects and contraindications are similar to other testosterone products.

Alternative Approaches

Alternatives to testosterone pellet implantation include observation without treatment, testosterone supplementation with injections or topical agents, or certain oral agents that may temporarily stimulate more testicular testosterone production.

What to do to Prepare for Procedure

You should temporarily stop blood-thinning medications, such as aspirin or fish oil, about seven days prior to the procedure.

What to Expect after Procedure

It is normal to have some tenderness, bruising, and blood spotting from the incision site for the first couple of days. Most men begin to experience symptom improvement after several weeks.